Endocrine Abstracts

Introduction: Primary hyperparathyroidism is an asymptomatic endocrine disorder in 80% of the cases. The bone manifestation represents the late stage of the disease and the brown tumor represents an exceptional and rare lesion.Observation: We report the case of a 73-year-old patient, with a medical history of type 2 diabetes, followed in the oto-rhino-laryngology department for a gingival tumor. A biopsy was performed and the anatomopathological examinat...

Introduction: Wermer syndrome or multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary disease characterized by the presence of generally benign tumors of the endocrine glands.Observation: We report the case of a 68-year-old patient with a family history of a sister having a primary hyperaldosteronism and a personal history of primary hyperaldosteronism who was referred to our department for the exploration of asymptomatic hypercalcemia. The bi...

Introduction: Glucagonomas are rare functioning pancreatic neuroendocrine tumours that secrete glucagon. Gastrinomas are neuroendocrine tumours that secrete gastrin and are rarely located in the stomach. We report an extremely rare case of concomitant gastric gastrinoma and glucagonoma.Case presentation: A 64-year-old-man with a history of digestive haemorrhage and gastrectomy presented with weight loss, asthenia, anorexia and abdominal pain. Esophagogas...

Introduction: Hyperprolactinemia is a common endocrine condition causing galactorrhoea. Breast abscess is a frequent complication of the post partum period and breast feeding but it rarely occurs out of these two situations. We report the case of a patient presenting with tumoural hyperprolactinaemia associated with a breast abscess.Case report: A 34 years-old patient presented with galactorrhoea, spaniomenorrhoea and headache for six months. She had not...

Introduction: Type 2 diabetes is a springboard to metabolic and cardiovascular complications. The objective of our work was to investigate the different cardiovascular risk factors in diabetic type 2 population, and study relation between the level of cardiovascular risk and the occurrence of degenerative complications.Patients and Methods: Retrospective study including 149 patients with type 2 diabetes consultant at the Department of Endocrinology at th...

Introduction: The coexistence of Grave disease [GD] and Myasthenia gravis [MG] may present a diagnostic dilemma especially concerning ocular manifestations. 3–10% of myasthenic patients exhibit GD, while MG is reported in only <1% of patients with thyroid disorder.Observation:Case 1: A 32-year-old woman, with a medical history of vitiligo, was diagnosed with GD. Immunology revealed positive anti-thyroid peroxidase antibod...

Introduction: Incidentally discovered adrenal incidentalomas has been reported to be as high as 5% of abdominal cross-sectional imaging performed for reasons unrelated to the adrenal gland. Although the management of bilateral and unilateral incidentalomas is the same, some studies suggest differences between the two groups.Patients and Methods: Retrospective study including 91 patients with adrenal incidentaloma at the Department of Endocrinology, Charl...

Introduction: Several familial disorders could be associated with adrenal pheochromocytoma such as Von Hippel–Lindau (VHL) syndrome, multiple endocrine neoplasia type 2 (MEN2) and, less commonly, neurofibromatosis type 1 (NF1). Herein, we report three cases of pheochromocytoma as a part of genetic syndromes.ObservationsPatient 1A 34-year-old women with no familial history, was diagnosed with severe hype...

Introduction: In 1974, the first case of concomitant thyroid and parathyroid disease was reported. Non-medullary thyroid carcinoma has been reported in 6% of patients with Primary hyperparathyroidism. However, the simultaneous occurrence of parathyroid carcinoma along with non-medullary thyroid carcinoma is extremely rare.Case report: We report a case of 60-year-old woman with a history of Diabetes Mellitus type 2 and hypertension. She had no family hist...

Introduction: Gougerot disease is an autoimmune disorder characterized by the lymphoid infiltration of salivary and lachrymal glands leading to the two most common symptoms dry eyes and a dry mouth. Primary hyperparathyroidism (PHPT), one of the most common endocrine disorders, is usually diagnosed by the association of hypercalcemia and parathyroid hormone (PTH) levels that are either elevated or inappropriately normal. The association of PHPT with Gougerot disease is rare, o...